Supreme is a free software library that performs automated super-resolution imaging.

The main technique employed is summarized in this paper. A more detailed description is given in my PhD dissertation

Input frame, 4x enlarged (data from the VGG group, with thanks to Barbara Levienaise-Obadia, Univ. of Surrey):

Simply stacking all 30 enlarged input images would yield:

The super-resolution result, based on the 30 input frames, using polygon interpolation is:

An article about computational science in a scientific publication is
not the scholarship itself, it is merely advertising of the scholarship.
 The actual scholarship is the complete software development environ-
ment and the complete set of instructions which generated the figures
 ―David L. Donoho, WaveLab and Reproducible Research, 1995, p. 5